Product Description: cGAS-IN-2 (compound 109) is a potent inhibitor of Cyclic GMP-AMP Synthase (cGAS), with IC50 of 0.01512 μM for h-cGAS[1].
Formula: C16H18Cl2N2O2
References: [1]Ventus Therapeutics U.S., Inc. Pyrido[4,3-b]indole derivatives and their use as pharmaceuticals. World Intellectual Property Organization, WO2022066851 A1 2022-03-31
CAS Number: 2765273-11-6
Molecular Weight: 341.23
Research Area: Inflammation/Immunology
Solubility: 10 mM in DMSO
Target: Cyclic GMP-AMP Synthase