Product Description: CGS 27023A is a non-peptidic and orally active MMP inhibitor with the Ki values of 43, 33, 20 and 8 nM for MMP-3, MMP-1, MMP-2 amd MMP-9, respectively. CGS 27023A can be used for study of arthritis[1].
Formula: C18H24ClN3O5S
References: [1]MacPherson LJ, et al. Discovery of CGS 27023A, a non-peptidic, potent, and orally active stromelysin inhibitor that blocks cartilage degradation in rabbits. J Med Chem. 1997;40(16):2525-2532.
CAS Number: 169799-04-6
Molecular Weight: 429.92
Research Area: Inflammation/Immunology
Solubility: 10 mM in DMSO
Target: MMP