CHIR-99021, CAS 252917-06-9

Description: CHIR-99021 (CT99021) is an activator of the Wnt/β-catenin signaling pathway and a GSK-3α/β inhibitor (IC50=10/6.7 nM) with selective and oral activity.CHIR-99021 induces cellular autophagy, which enhances self-renewal in mouse and human embryonic stem cells.

CAS Number: 252917-06-9

Formula: C22H18Cl2N8

Molecular Weight: 465,34

References: Naujok O, et al. Cytotoxicity and activation of the Wnt/beta-catenin pathway in mouse embryonic stem cells treated with four GSK3 inhibitors. BMC Res Notes. 2014 Apr 29;7:273.

• SKU: TGMT2310-10mg
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T2310-10mg
• Package Unit: 10 mg
• Quantity Unit: STK