Product Description: CIDD-0072424 selectively inhibits Protein Kinase C-epsilon (PKCε) (Ki = 54 nM). CIDD-0072424 reduces ethanol consumption and preference in a dose-dependent manner[1].
Formula: C24H29ClN4O2
References: [1]De Kraker H, et al. Asymmetric Synthesis of CIDD-0072424 via an Enantioselective Nitro-Mannich Reaction: A Central Nervous System Penetrant, Selective Small Molecule Inhibitor of Protein Kinase C Epsilon. J Org Chem. 2024 Apr 5;89(7):5134-5141.