Product Description: Cilnidipine (Standard) is the analytical standard of Cilnidipine. This product is intended for research and analytical applications. Cilnidipine is a long-acting, second-generation dihydropyridine Ca2+-channel blocker on L and N-type Ca2+ channel[1][2][3][4]. Antihypertensive effects[5].
Formula: N/A
References: [1]A Takahara, et al. [Antihypertensive effects of repeated oral administration of cilnidipine, a novel calcium antagonist, in 2K1C renal hypertensive dogs]. Nihon Yakurigaku Zasshi. 1995 Oct;106(4):279-87./[2] S Fujii,et al. Effect of cilnidipine, a novel dihydropyridine Ca<sup>2+</sup>-channel antagonist, on N-type Ca<sup>2+</sup> channel in rat dorsal root ganglion neurons. J Pharmacol Exp Ther. 1997 Mar;280(3):1184-91./[3]Matthias Löhn, et al. Cilnidipine is a novel slow-acting blocker of vascular L-type calcium channels that does not target protein kinase C. J Hypertens. 2002 May;20(5):885-93./[4]Young Joo Lee, et al. Cilnidipine mediates a neuroprotective effect by scavenging free radicals and activating the phosphatidylinositol 3-kinase pathway. J Neurochem. 2009 Oct;111(1):90-100./[5]Naresh Kumar, et al. Anti-stress effects of cilnidipine and nimodipine in immobilization subjected mice. Physiol Behav. 2012 Mar 20;105(5):1148-55.
CAS Number: 132203-70-4
Molecular Weight: N/A
Research Area: Cardiovascular Disease
Target: Calcium Channel
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