Cloxacepride, CAS 65569-29-1

Product Description: Cloxacepride is an orally active and potent antiallergic agent. Cloxacepride is a CaM (calmodulin) antagonist. Cloxacepride has anti-PCA (passive cutaneous anaphylaxis) activity[1][2].

Applications: COVID-19-immunoregulation

Formula: C22H27Cl2N3O4

References: [1]Gigl G, et al. Calmodulin antagonism: a pharmacological approach for the inhibition of mediator release from mast cells. Cell Calcium. 1987 Oct;8(5):327-44./[2]Friedrich G, et al. Inhibitory effect of cloxacepride on compound 48/80-induced histamine and serotonin release from rat mast cells. Arch Int Pharmacodyn Ther. 1984 Feb;267(2):264-8. /[3]Metz G, et al. Cloxacepride and related compounds: a new series of orally active antiallergic compounds. J Med Chem. 1983 Jul;26(7):1065-70.

CAS Number: 65569-29-1

Molecular Weight: 468.37

Research Area: Inflammation/Immunology; Neurological Disease

Solubility: 10 mM in DMSO

Target: Calmodulin

• SKU: MEXHY-106645-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-106645-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK