CLOZAPINE N-OXIDE, CAS 34233-69-7

Description: Clozapine N-oxide is the major metabolite of Clozapine and is blood-brain barrier permeable. Clozapine N-oxide is an agonist of DREADDs and activates the DREADD receptors hM3Dq and hM4Di. Clozapine N-oxide is also a dopamine antagonist and selective muscarinic M4 receptor agonist.

CAS Number: 34233-69-7

Formula: C18H19ClN4O

Molecular Weight: 342,82

References: Jendryka M, et al. Pharmacokinetic and pharmacodynamic actions of clozapine-N-oxide, clozapine, and compound 21 in DREADD-based chemogenetics in mice. Sci Rep. 2019 Mar 14;9(1):4522.

• SKU: TGMT4494-50mg
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T4494-50mg
• Package Unit: 50 mg
• Quantity Unit: STK