Product Description: CMPF can be found in trace constituent of urine and blood. CMPF is a biomarker of type 2 diabetes. CMPF can act on the β cell and induces impaired mitochondrial function. CMPF decreases glucose-induced ATP accumulation, and induces oxidative stress. CMPF reverses hepatic lipid accumulation and improves insulin sensitivity in obese mice[1][2].
Applications: Metabolism-sugar/lipid metabolism
Formula: C12H16O5
References: [1]Prentice KJ, et al. The furan fatty acid metabolite CMPF is elevated in diabetes and induces β cell dysfunction. Cell Metab. 2014 Apr 1;19(4):653-66./[2]Prentice KJ, et al. CMPF, a Metabolite Formed Upon Prescription Omega-3-Acid Ethyl Ester Supplementation, Prevents and Reverses Steatosis. EBioMedicine. 2018 Jan;27:200-213.
CAS Number: 86879-39-2
Molecular Weight: 240.25
Compound Purity: 99.57
Research Area: Metabolic Disease
Solubility: DMSO : 250 mg/mL (ultrasonic)
Target: Endogenous Metabolite
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