CNB-001, CAS 1019110-87-2

Product Description: CNB-001 is a potent 5-lipoxygenase (5-LOX) inhibitor, decreases 5-LOX expression, and increases proteasome activity. CNB-001 also increases eIF2α phosphorylation and HSP90 and ATF4 levels in Alzheimer's disease transgenic mice, and limits the accumulation of soluble Aβ and ubiquitinated aggregated proteins. CNB-001 maintains the expression of synapse-associated proteins and improves memory. CNB-001 can be used for the research of Alzheimer's disease[1].

Formula: C27H24N2O4

References: [1]Valera E, et al. Modulation of 5-lipoxygenase in proteotoxicity and Alzheimer's disease. J Neurosci. 2013 Jun 19;33(25):10512-25.

CAS Number: 1019110-87-2

Molecular Weight: 440.49

Research Area: Neurological Disease

Solubility: 10 mM in DMSO

Target: Lipoxygenase

• SKU: MEXHY-158204-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-158204-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK