COP1-ATGL modulator 1, CAS 2946701-09-1

Product Description: COP1-ATGL modulator 1 (86) is an orally active modulator for COP1-ATGL axis. COP1-ATGL modulator 1 (86) could increase ATGL protein expression, reduce ATGL ubiquitination and COP1 autoubiquitination, and diminish lipid accumulation in hepatocytes in the nanomolar range[1].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C27H33N5O5

References: [1]Dipayan Sarkar, et al. Discovery and Development of Quinazolinones and Quinazolinediones for Ameliorating Nonalcoholic Fatty Liver Disease (NAFLD) by Modulating COP1-ATGL Axis. J Med Chem. 2023 Dec 28;66(24):16728-16761.

CAS Number: 2946701-09-1

Molecular Weight: 507.58

Compound Purity: 99.31

Research Area: Metabolic Disease

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Others

• SKU: MEXHY-157416-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-157416-25
• Green Labware: No
• Package Unit: 25 mg
• Quantity Unit: STK