CP-289,503, CAS 1349637-14-4

Product Description: CP-289,503 is an inhibitor of the complement C5a receptor with an IC50 of 1 μM. C5a acts as an activator of leukocytes and phagocytes during complement system activation. The C5a receptor can bind to C5a, which can stimulate the upregulation of cell surface integrins and degranulation of inflammatory cells, leading to endothelial cell damage. C5a receptor inhibitors can block C5a signaling and inhibit a variety of inflammatory diseases[1].

Applications: COVID-19-immunoregulation

Formula: C30H35ClN2O2

References: [1]Blagg J, et al. Small, non-peptide C5a receptor antagonists: part 1. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5601-4.

CAS Number: 1349637-14-4

Molecular Weight: 491.06

Research Area: Inflammation/Immunology

Target: Complement System

• SKU: MEXHY-160901-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-160901-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK