Product Description: CP-346086 is a potent and orally active microsomal triglyceride transfer protein (MTP) inhibitor, with an IC50 of 2.0 nM for human and rodent MTP. CP-346086 can lower plasma cholesterol and triglycerides in vivo[1].
Applications: Metabolism-sugar/lipid metabolism
Formula: C26H22F3N5O
References: [1]Chandler CE, et, al. CP-346086: an MTP inhibitor that lowers plasma cholesterol and triglycerides in experimental animals and in humans. J Lipid Res. 2003 Oct;44(10):1887-901.
CAS Number: 186390-48-7
Molecular Weight: 477.48
Compound Purity: 99.16
Research Area: Metabolic Disease
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: Microsomal Triglyceride Transfer Protein (MTP)