Crobenetine, CAS 221019-25-6

Product Description: Crobenetine (BIII-890), a benzomorphan derivative, is a potent, selective, and highly use-dependent Na+ channel blocker. Crobenetine displaces [3H]BTX from site 2 of the Na+ channel (IC50=49 nM) in rat brain synaptosomes, yet exhibits only low binding affinity for other receptors and ion channels. Crobenetine protects brain tissue from the deleterious effects of focal cerebral ischemia in rodents[1].

Applications: Neuroscience-Neuromodulation

Formula: C25H33NO2

References: [1]A J Carter, et al. Potent blockade of sodium channels and protection of brain tissue from ischemia by BIII 890 CL. Proc Natl Acad Sci U S A. 2000 Apr 25;97(9):4944-9.

CAS Number: 221019-25-6

Molecular Weight: 379.54

Research Area: Neurological Disease

Target: Sodium Channel

• SKU: MEXHY-16923-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-16923-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK