Product Description: Custirsen sodium is a highly specific antisense oligonucleotide that inhibits the production of clusterin , an antiapoptotic protein that is upregulated in response to chemotherapy and that confers treatment resistance.
Applications: Cancer-programmed cell death
Formula: C231H292N78Na20O119P20S20
References: [1]Chi KN, Eisenhauer E, Fazli L, et al. A phase I pharmacokinetic and pharmacodynamic study of OGX-011, a 2'-methoxyethyl antisense oligonucleotide to clusterin, in patients with localized prostate cancer. J Natl Cancer Inst. 2005;97(17):1287-1296.
Molecular Weight: 7786.00
Compound Purity: 98.71
Research Area: Cancer
Solubility: 10 mM in H2O
Target: Apoptosis