CYP1B1-IN-8

Product Description: CYP1B1-IN-8 (Compound 14b) is a CYP1B1 inhibitor (IC50: 4.14 × 10–5 nM). CYP1B1-IN-8 reduces the resistance in A549 cells to Paclitaxel (HY-B0015), and inhibits cell migration and invasion[1].

Formula: C16H15ClIN3

References: [1]Yang M, et al. Design of Novel 2-Phenylquinazolin-4-amines as Selective CYP1B1 Inhibitors for Overcoming Paclitaxel Resistance in A549 Cells. J Med Chem. 2024 Apr 11;67(7):5883-5901.

Molecular Weight: 411.67

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Cytochrome P450

• SKU: MEXHY-161403-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-161403-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK