Darunavir (Ethanolate), CAS 635728-49-3

Product Description: Darunavir ethanolate (TMC114 Ethanolate) is a potent HIV protease inhibitor used to treat and prevent HIV/AIDS. Darunavir has a Ki of 1 nM for wild type HIV-1 protease.

Applications: COVID-19-anti-virus

Formula: C29H43N3O8S

References: [1]Tie Y, et al. High resolution crystal structures of HIV-1 protease with a potent non-peptide inhibitor (UIC-94017) active against multi-drug-resistant clinical strains. J Mol Biol. 2004 Apr 23;338(2):341-52./[2]McKeage K, et al. Darunavir: a review of its use in the management of HIV infection in adults. Drugs. 2009;69(4):477-503./[3]Bhalekar MR, et al. In-vivo bioavailability and lymphatic uptake evaluation of lipid nanoparticulates of darunavir. Drug Deliv. 2016 Sep;23(7):2581-2586.

CAS Number: 635728-49-3

Molecular Weight: 593.73

Compound Purity: 99.81

Research Area: Infection

Solubility: DMSO : ≥ 50 mg/mL

Target: HIV;HIV Protease

• SKU: MEXHY-17041-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-17041-25
• Green Labware: No
• Package Unit: 25 mg
• Quantity Unit: STK