dBRD4-BD1, CAS 2839318-19-1

Product Description: dBRD4-BD1 is a selective and durable BRD4 degrader with an DC50 value of 280 nM (Dmax=77%). dBRD4-BD1 upregulates BRD2/3 protein level and shows low cytotoxicity than iBRD4-BD1[1].

Applications: Cancer-programmed cell death

Formula: C50H53F3N8O9

References: [1]Divakaran A, et al. Development of an N-Terminal BRD4 Bromodomain-Targeted Degrader. ACS Med Chem Lett. 2022 Sep 29;13(10):1621-1627.

CAS Number: 2839318-19-1

Molecular Weight: 967.00

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Epigenetic Reader Domain;PROTACs

• SKU: MEXHY-151593-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-151593-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK