DNA gyrase B-IN-2

Product Description: DNA gyrase B-IN-2 (Compound E) is a 2-aminobenzothiazole-based DNA gyrase B inhibitor with promising activity against ESKAPE bacterial pathogens. DNA gyrase B-IN-2 showed low nanomolar inhibition of DNA gyrase (IC50 E. coli, Acinetobacter baumannii, Pseudomonas aeruginosa, and Klebsiella pneumoniae.DNA gyrase B-IN-2 can be used for the research of infection[1].

Formula: C18H18Cl2N4O4S

References: [1]Sterle M, et al. Exploring the 5-Substituted 2-Aminobenzothiazole-Based DNA Gyrase B Inhibitors Active against ESKAPE Pathogens. ACS Omega. 2023 Jun 28;8(27):24387-24395.

Molecular Weight: 457.33

Compound Purity: 99.77

Research Area: Infection

Solubility: 10 mM in DMSO

Target: Bacterial

• SKU: MEXHY-155007-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-155007-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK