DNMT/HDAC-IN-1, CAS 2095619-17-1

Product Description: DNMT/HDAC-IN-1 (Compund 15a) is a dual DNMT and HDAC inhibitor with IC50 values for HDAC1 and HDAC6 are 56.84 nM and 17.39 nM respectively. DNMT/HDAC-IN-1 can induce apoptosis and be used in tumor research.

Applications: Cancer-programmed cell death

Formula: C19H16ClF3N2O3

References: [1]Yuan Z, et al. Design, synthesis and anticancer potential of NSC-319745 hydroxamic acid derivatives as DNMT and HDAC inhibitors. Eur J Med Chem. 2017 Jul 7;134:281-292./[2]Huang W, et al. Dual inhibitors of DNMT and HDAC induce viral mimicry to induce antitumour immunity in breast cancer. Cell Death Discov. 2024 Mar 15;10(1):143.

CAS Number: 2095619-17-1

Molecular Weight: 412.79

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: DNA Methyltransferase;HDAC

• SKU: MEXHY-158075-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-158075-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK