DNMT3A-IN-2

Product Description: DNMT3A-IN-2 (compound 1a) is a hydrophthalazinone-based inhibitor of DNA methyltransferase 3A (DNMT3A) (IC50: 14 μM) against S-adenosylmethionine (SAM) has a Ki of 9.16-18.85 μM.[14][1].

Applications: Cancer-programmed cell death

Formula: C33H40N6O4

References: [1]Hernandez I, et al. Structural Investigations of Phthalazinone Derivatives as Allosteric Inhibitors of Human DNA Methyltransferase 3A[J]. ACS Medicinal Chemistry Letters, 2024.

Molecular Weight: 584.71

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: DNA Methyltransferase

• SKU: MEXHY-158164-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-158164-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK