Product Description: Doripenem (S 4661), a 1β-methyl parenteral carbapenem, has very broad-spectrum activity against Gram-positive and Gram-negative aerobic bacteria[1][2].
Applications: COVID-19-immunoregulation
Formula: C15H24N4O6S2
Citations: Antimicrob Agents Chemother. 2023 May 18;e0160322./Biomed Res Int. 2018 Jul 2;2018:3579832. /Microbiol Spectr. 2022 Dec 8;e0303822./Microbiol Spectr. 2023 Apr 24;e0069223./Antimicrob Agents Chemother. 2018 May 25;62(6). pii: e00282-18.
References: [1]Jones RN, et al. Doripenem (S-4661), a novel carbapenem: comparative activity against contemporary pathogens including bactericidal action and preliminary in vitro methods evaluations. J Antimicrob Chemother. 2004 Jul;54(1):144-54. Epub 2004 Jun 9./[2]Aryun Kim, et al. In vivo pharmacodynamic profiling of doripenem against Pseudomonas aeruginosa by simulating human exposures. Antimicrob Agents Chemother. 2008 Jul;52(7):2497-502.
CAS Number: 148016-81-3
Molecular Weight: 420.50
Compound Purity: 99.90
Research Area: Infection
Solubility: 10 mM in DMSO
Target: Antibiotic;Bacterial