Dorsomorphin, CAS 866405-64-3

Description: Dorsomorphin (BML-275) is an AMPK inhibitor (Ki=109 nM) that is selective and ATP-competitive. Dorsomorphin inhibits the BMP type I receptors ALK2, ALK3, and ALK6. Dorsomorphin induces autophagy, and possesses antitumor activity.

CAS Number: 866405-64-3

Formula: C24H25N5O

Molecular Weight: 399,49

References: Li N, et al. Dorsomorphin induces cancer cell apoptosis and sensitizes cancer cells to HSP90 and proteasome inhibitors by reducing nuclear heat shock factor 1 levels. Cancer Biol Med. 2019 May;16(2):220-233.

• SKU: TGMT1977-10mg
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T1977-10mg
• Package Unit: 10 mg
• Quantity Unit: STK