Product Description: DRP1i27 is a potent inhibitor of human Drp1 (dynamin-related protein 1). DRP1i27 binds to the GTPase site of Drp1, with hydrogen bonds to Gln34 and Asp218. DRP1i27 targets Drp1-mediated mitochondrial fission in cell line models and protects against simulated ischemia-reperfusion injury[1].
Applications: Neuroscience-Neuromodulation
Formula: C20H26N6O
References: [1]Rosdah AA, et al. A novel small molecule inhibitor of human Drp1. Sci Rep. 2022 Dec 13;12(1):21531.