DS-1-38

Product Description: DS-1-38 is an EYA1 antagonist that blocks Sonic Hedgehog (SHH) signaling. EYA1 is a haloacid dehalogenase phosphatase and transcription factor that regulates tumorigenesis and proliferation in SHH medulloblastoma (SHH-MB)[1].

Formula: C21H18N2O3

References: [1]Hwang GH, et al. A Benzarone Derivative Inhibits EYA to Suppress Tumor Growth in SHH Medulloblastoma. Cancer Res. 2024 Mar 15;84(6):872-886.

Molecular Weight: 346.38

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Hedgehog

• SKU: MEXHY-158059-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-158059-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK