Product Description: DV-B-120 is a competitive inhibitor for dengue virus (DENV) with IC50s of 5.35, 7.39, 10.49 and 8.58 μM, for DENV-1, DENV-2, DENV-3 and DENV-4, respectively, by inhibiting NS2B-NS3 protease. DV-B-120 exhibits antiviral activity through inhibition of DENV replication[1].
Formula: C23H18N2O5S2
References: [1]Huang Y-J, et al., Exploring the therapeutic potential of DV-B-120 as an inhibitor of dengue virus infection. J Virol. 2024 Apr 16;98(4):e0125823.
Molecular Weight: 466.53
Research Area: Infection
Solubility: 10 mM in DMSO
Target: Dengue virus;Virus Protease