DXR-IN-1

Product Description: DXR-IN-1 (Compound 13E) is an inhibitor of 1-deoxy-D-ketose 5-phosphate reductoisomerase (DXR). DXR-IN-1 is highly selective for P. falciparum DXR (IC50=0.030 μM). DXR-IN-1 inhibits the growth of P. falciparum by binding to the active site of DXR and blocking its catalytic activity[1].

Formula: C19H24NO5P

References: [1]Abdullaziz MA et al. Reverse N-Substituted Hydroxamic Acid Derivatives of Fosmidomycin Target a Previously Unknown Subpocket of 1-Deoxy-d-xylulose 5-Phosphate Reductoisomerase (DXR). ACS Infect Dis. 2024 May 10;10(5):1739-1752.

Molecular Weight: 377.37

Research Area: Infection

Solubility: 10 mM in DMSO

Target: Parasite

• SKU: MEXHY-158335-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-158335-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK