Description: Dynasore (Dynamin Inhibitor I), a cell-permeable chemical, can reversibly and non-competitivity inhibit GTPase activity of dynamin 1/2 (IC50: 15 μM in a cell-free assay). It also inhibits the mitochondrial dynamin Drp1, with no effect against other small GTPase.
CAS Number: 304448-55-3
Formula: C18H14N2O4
Molecular Weight: 322,31
References: Macia E, et al. Dev Cell, 2006, 10(6), 839-850.