(E)-KN-93 (phosphate), CAS 1188890-41-6

Product Description: (E)-KN-93 phosphate is an inhibitor for Ca2+/calmodulin-dependent protein kinase II (CaMK II) with IC50 of 9 μM and 3 μM, for CaMKIIδ monomer and CaMKIIδ dodecamer. (E)-KN-93 phosphate binds competitively with Ca2+/CaM, and disrupts their interaction with CaMK II, and thus inhibits the CaMK II activation[1].

Formula: C26H32ClN2O8PS

References: [1]Wong MH, et al., The KN-93 Molecule Inhibits Calcium/Calmodulin-Dependent Protein Kinase II (CaMKII) Activity by Binding to Ca2+/CaM. J Mol Biol. 2019 Mar 29;431(7):1440-1459.

CAS Number: 1188890-41-6

Molecular Weight: 599.03

Research Area: Neurological Disease; Cardiovascular Disease

Solubility: 10 mM in DMSO

Target: CaMK

• SKU: MEXHY-110140-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-110140-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK