(E/Z)-SIS3 (free base), CAS 1009104-85-1

Product Description: E/Z-SIS3 free base exhibits an inhibitory efficacy against smad3, exhibits an anti-fibrotic and anti-inflammatory effect through a TGF-β/smad3 signaling pathway[1].

Applications: COVID-19-immunoregulation

Formula: C28H27N3O3

References: [1]Shou J, et al., SIS3, a specific inhibitor of smad3, attenuates bleomycin-induced pulmonary fibrosis in mice. Biochem Biophys Res Commun. 2018 Sep 5;503(2):757-762.

CAS Number: 1009104-85-1

Molecular Weight: 453.53

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: TGF-beta/Smad

• SKU: MEXHY-W803134-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W803134-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK