Ebselen derivative 1, CAS 3030492-59-9

Product Description: Ebselen derivative 1 (Compound 19) is a glutathione peroxidase (GPx) mimic with oral activity. Ebselen derivative 1 demonstrates significant protective effects against cisplatin (HY-17394)-induced hair cell (HC) damage both in vitro and in vivo, effectively reducing oxidative stress, apoptosis, and ferroptosis in hair cells. Ebselen derivative 1 can be utilized in the research of cisplatin (HY-17394)-induced hearing loss [1].

Formula: C13H10N2O2Se

References: [1]Wang W, et al. Quantum chemistry calculation-aided discovery of potent small-molecule mimics of glutathione peroxidases for the treatment of cisplatin-induced hearing loss. Eur J Med Chem. 2024;271:116404.

CAS Number: 3030492-59-9

Molecular Weight: 305.19

Research Area: Others

Solubility: 10 mM in DMSO

Target: Apoptosis

• SKU: MEXHY-163506-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-163506-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK