Product Description: Edonerpic maleate is a novel neurotrophic agent which can inhibit amyloid-β peptides (Aβ).
Applications: Neuroscience-Neurodegeneration
Formula: C20H25NO6S
References: [1]Hirata K, et al. A novel neurotrophic agent, T-817MA [1-{3-[2-(1-benzothiophen-5-yl) ethoxy] propyl}-3-azetidinol maleate], attenuates amyloid-beta-induced neurotoxicity and promotes neurite outgrowth in rat cultured central nervous system neurons. J Pharmacol Exp Ther. 2005 Jul;314(1):252-9./[2]Kimura T, et al. T-817MA, a neurotrophic agent, ameliorates the deficits in adult neurogenesis and spatial memory in rats infused i.c.v. with amyloid-beta peptide. Br J Pharmacol. 2009 Jun;157(3):451-63.
CAS Number: 519187-97-4
Molecular Weight: 407.48
Compound Purity: 99.79
Research Area: Neurological Disease
Solubility: DMSO : 100 mg/mL (ultrasonic)/H2O : 100 mg/mL (ultrasonic)
Target: Amyloid-β
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