Product Description: Elobixibat hydrate is a potent ileal bile acid transporter (IBAT) inhibitor, with IC50 values of 0.53 ± 0.17 nM, 0.13 ± 0.03 nM, and 5.8 ± 1.6 nM for human IBAT, mouse IBAT, and canine IBAT. Elobixibat hydrate can be used for chronic idiopathic constipation (CIC) research[1].
Applications: Metabolism-protein/nucleotide metabolism
Formula: C36H47N3O8S2
References: [1]Wong BS, et al. Elobixibat for the treatment of constipation. Expert Opin Investig Drugs. 2013 Feb; 22(2):277-84.
CAS Number: 1633824-78-8
Molecular Weight: 713.90
Compound Purity: 99.44
Research Area: Metabolic Disease
Solubility: 10 mM in DMSO
Target: Apical Sodium-Dependent Bile Acid Transporter