Product Description: ELQ-598, as a prodrug, is converted into the active drug ELQ-596 upon oral administration. ELQ-598 demonstrates potent parasitic growth inhibition capabilities (IC50= 37 nM). ELQ-598 also shows low toxicity towards human cells (IC50= 19 μM). ELQ-598 can be used for research into babesiosis[1].
Applications: COVID-19-immunoregulation
Formula: C28H23ClF3NO6
References: [1]Vydyam P, et al. Effectiveness of Two New Endochin-like Quinolones, ELQ-596 and ELQ-650, in Experimental Mouse Models of Human Babesiosis. ACS Infect Dis. 2024 Apr 12;10(4):1405-1413.
CAS Number: 3023709-99-8
Molecular Weight: 561.93
Research Area: Others
Solubility: 10 mM in DMSO
Target: Parasite