Description: Enzalutamide (MDV3100) is an androgen receptor (AR) antagonist (IC50=36 nM in LNCaP). Enzalutamide activates autophagy, has antitumor activity, and is commonly used in the treatment of desmoplasia-resistant prostate cancer.
CAS Number: 915087-33-1
Formula: C21H16F4N4O2S
Molecular Weight: 464,44
References: Wright TC, et al. Abiraterone In Vitro Is Superior to Enzalutamide in Response to Ionizing Radiation. Front Oncol. 2021 Jul 21;11:700543.