EZH2-IN-17, CAS 2489672-09-3

Product Description: EZH2-IN-17 (compound 28) is a potent and orally active EZH2 inhibitor with an IC50 value of 0.95 nM. EZH2-IN-17 exhibits high anti-proliferation activity against different lymphoma cell lines including WSU-DLCL2, Pfeiffer and Karpas-422 (IC50 values of 2.36 nM, 1.73 nM, and 1.82 nM, respectively)[1].

Applications: Cancer-programmed cell death

Formula: C36H46N4O4

References: [1]Xin Xu, et al. Conformationally constrained potent inhibitors for enhancer of zeste homolog 2 (EZH2). Bioorg Med Chem Lett. 2023 Nov 11:129558.

CAS Number: 2489672-09-3

Molecular Weight: 598.77

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Histone Methyltransferase

• SKU: MEXHY-149726-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-149726-25
• Green Labware: No
• Package Unit: 25 mg
• Quantity Unit: STK