FAZ-3532

Product Description: FAZ-3532 (compound G3Ia) is an inhibitor of binding to the NTF2L domain of G3BP1/2 that binds to G3BP1 with a Kd of 0.54 μM. FAZ-3532 targets the protein-protein interaction domain of G3BP1/2 and specifically inhibits co-condensation of G3BP1, caprin 1, and RNA in vitro[1].

Formula: C38H56FN5O7

References: [1]Brian D Freibaum, et al. Identification of small molecule inhibitors of G3BP-driven stress granule formation. J Cell Biol. 2024 Mar 4;223(3):e202308083.

Molecular Weight: 713.88

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Others

• SKU: MEXHY-162288-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-162288-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK