FAZ-3780

Product Description: FAZ-3780 (compound G3Ib) is an inhibitor of binding to the NTF2L domain of G3BP1/2 that binds to G3BP1 with a Kd of 0.15 μM. FAZ-3780 targets the protein-protein interaction domain of G3BP1/2 and specifically inhibits co-condensation of G3BP1, caprin 1, and RNA in vitro[1].

Applications: Cancer-programmed cell death

Formula: C35H50N4O5

References: [1]Brian D Freibaum, et al. Identification of small molecule inhibitors of G3BP-driven stress granule formation. J Cell Biol. 2024 Mar 4;223(3):e202308083.

Molecular Weight: 606.80

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Others

• SKU: MEXHY-162289-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-162289-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK