FB49

Product Description: FB49 is a highly selective inhibitor of Bcl-2-associated athanogene 3 (BAG3), with the Ki of 45 μM. FB49 inhibits the cell growth in human tumoral cells, but has no toxicity in human peripheral mononuclear cells. FB49 block cell cycle in G1 phase and to induce apoptosis as well as autophagy in medulloblastoma HD-MB03 treated cells[1].

Formula: C17H18N2O6S

References: [1]Budassi F, et al. Design, synthesis and biological evaluation of novel 2,4-thiazolidinedione derivatives able to target the human BAG3 protein [published online ahead of print, 2023 Sep 22]. Eur J Med Chem. 2023;261:115824.

Molecular Weight: 378.40

Compound Purity: 99.76

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Apoptosis;Autophagy

• SKU: MEXHY-156278-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-156278-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK