Product Description: Fluorofolin is a dihydrofolate reductase (DHFR) inhibitor with an IC50 of 2.5 nM. Fluorofolin exhibits significant activity against P. aeruginosa[1].
Formula: C16H13FN6
References: [1]Connor Chain, et al. A folate inhibitor exploits metabolic differences in Pseudomonas aeruginosa for narrow-spectrum targeting. Nat Microbiol. 2024 May;9(5):1207-1219.