FR260330, CAS 442198-67-6

Product Description: FR260330 is a selective, orally active inhibitor for inducible nitric oxide synthase (iNOS) through suppression of iNOS dimerization. FR260330 inhibits the NO accumulation in rat splenocytes and human DLD-110 cells, with IC50 of 27 and 10 nM. FR260330 ameliorates the Lipopolysaccharides (HY-D1056)-induced inflammatory diseases in rats model[1].

Applications: COVID-19-immunoregulation

Formula: C29H28ClF3N6O4

References: [1]Chida N, et al., Pharmacological profile of FR260330, a novel orally active inducible nitric oxide synthase inhibitor. Eur J Pharmacol. 2005 Feb 10;509(1):71-6.

CAS Number: 442198-67-6

Molecular Weight: 617.02

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: NO Synthase

• SKU: MEXHY-122063-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-122063-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK