FXR agonist 7

Product Description: FXR agonist 7 (compound 33) is a potent agonist of FXR, with EC50 of 0.1 nM. FXR agonist 7 shows high intestinal distribution, good anti-inflammatory activity[1].

Formula: C34H36F3N3O5

References: [1]Yuan Li, et al. Discovery and Optimization of Novel Nonbile Acid FXR Agonists as Preclinical Candidates for the Treatment of Inflammatory Bowel Disease. J Med Chem. 2024 Apr 11;67(7):5642-5661.

Molecular Weight: 623.66

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: FXR

• SKU: MEXHY-163466-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-163466-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK