Product Description: Gentisuric acid, a metabolite of Aspirin (HY-14654), is a substrate of α-amidating monooxygenase (PAM). Gentisuric acid prevents DNA-damage by Mitomycin C (HY-13316)[1][2].
Formula: C9H9NO5
References: [1]DeBlassio JL, et al. Amidation of salicyluric acid and gentisuric acid: a possible role for peptidylglycine alpha-amidating monooxygenase in the metabolism of aspirin. Arch Biochem Biophys. 2000 Nov 1;383(1):46-55./[2]Niikawa M, et al. Suppressive effect of post- or pre-treatment of aspirin metabolite on mitomycin C-induced genotoxicity using the somatic mutation and recombination test in Drosophila melanogaster. Biomed Pharmacother. 2007 Feb-Apr;61(2-3):113-9.
CAS Number: 25351-24-0
Molecular Weight: 211.17
Compound Purity: 99.65
Research Area: Cancer
Solubility: DMSO : 83.33 mg/mL (ultrasonic)
Target: Drug Metabolite
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