Product Description: Globomycin derivative G2A (Compound G2A) is an inhibitor for lipoprotein signal peptidase II (LspA), with an IC50 of 604 nM. Globomycin derivative G2A inhibits E. coli, P. aeruginosa and A. baumannii, with MIC ranging from 12.5 to 32 μg/mL[1].
Applications: COVID-19-immunoregulation
Formula: C34H62N6O8
References: [1]Craven TW, et al., Computational Design of Cyclic Peptide Inhibitors of a Bacterial Membrane Lipoprotein Peptidase. ACS Chem Biol. 2024 May 17;19(5):1125-1130.
Molecular Weight: 682.89
Research Area: Infection
Solubility: 10 mM in DMSO
Target: Bacterial