Product Description: Graveoline (Rutamine) is an anti-cancer agent that can trigger apoptosis and autophagy in skin melanoma cells. Graveoline also exhibits antifungal activity[1].
Formula: C17H13NO3
References: [1]Ghosh S, et, al. Graveoline isolated from ethanolic extract of Ruta graveolens triggers apoptosis and autophagy in skin melanoma cells: a novel apoptosis-independent autophagic signaling pathway. Phytother Res. 2014 Aug;28(8):1153-62./[2]Kamal LZM, et, al. Identification of Alkaloid Compounds Arborinine and Graveoline from Ruta angustifolia (L.) Pers for their Antifungal Potential against Isocitrate lyase (ICL1) gene of Candida albicans. Mycopathologia. 2021 May;186(2):221-236.
CAS Number: 485-61-0
Molecular Weight: 279.29
Compound Purity: 99.96
Research Area: Cancer; Infection
Solubility: DMSO : 20 mg/mL (ultrasonic;warming;heat to 60°C)
Target: Apoptosis;Autophagy;Fungal