H3B-8800, CAS 1825302-42-8

Product Description: H3B-8800 is a potent and orally active SF3B splicing modulator. H3B-8800 direct interaction with the SF3b complex and shows anti-cancer activity. H3B-8800 has the potential for the research of acute myeloid leukemia (AML) with SF3B1 mutant[1].

Formula: C31H45N3O6

References: [1]Seiler M, et al. H3B-8800, an orally available small-molecule splicing modulator, induces lethality in spliceosome-mutant cancers. Nat Med. 2018 May;24(4):497-504.

CAS Number: 1825302-42-8

Molecular Weight: 555.71

Compound Purity: 98.18

Research Area: Cancer

Solubility: DMSO : ≥ 100 mg/mL

Target: Apoptosis;DNA/RNA Synthesis

• SKU: MEXHY-111517-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-111517-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK