Product Description: Halociline, a derivative of alkaloids, that can be isolated from the marine fungus Penicillium griseofulvum.Halociline targets MAPK1, MMP-9, and PIK3CA in gastric cancer cells, potentially mediated by diverse pathways including cancer, lipid metabolism, atherosclerosis, and EGFR tyrosine kinase inhibitor resistance. Halociline possesses antimicrobial, antioxidant and biofilm inhibitory activities[1][2].
Applications: COVID-19-immunoregulation
Formula: C11H17NO2
References: [1]Mohamed M M Abdel Razek, et al. A New Phenolic Alkaloid from Halocnemum strobilaceum Endophytes: Antimicrobial, Antioxidant and Biofilm Inhibitory Activities. Chem Biodivers. 2020 Oct;17(10):e2000496./[2]Xiangru Zha, et al. Network pharmacology, molecular docking, and molecular dynamics simulation analysis reveal the molecular mechanism of halociline against gastric cancer. Mol Divers. 2024 Mar 19.
CAS Number: 2977255-36-8
Molecular Weight: 195.26
Research Area: Cancer; Infection; Inflammation/Immunology
Solubility: 10 mM in DMSO
Target: MMP;p38 MAPK
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