Product Description: HDAC6-IN-41 (Compound E24) is a selective inhibitor for histone deacetylase 6 (HDAC6), with IC50 of 14 and 422 nM, for HDAC6 and HDAC8, respectively. HDAC6-IN-41 upregulates the acetylation of α-tubulin and histone site SMC3[1].
Applications: Cancer-programmed cell death
Formula: C16H12N2O6S
References: [1]Hansen T N, et al., Sulfur (VI) Fluoride Exchange Chemistry in Solid-Phase Synthesis of Compound Arrays: Discovery of Histone Deacetylase Inhibitors[J]. JACS Au, 2024.
Molecular Weight: 360.34
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: HDAC