Product Description: HGPRT/TBrHGPRT1-IN-1 (Compound 5) is a selective inhibitor targeting human hypoxanthine-guanine phosphoribosyltransferase (HGPRT) and Trypanosoma bruce HGPRT1 (TBrHGPRT1) (both Ki=3 nM). HGPRT/TBrHGPRT1-IN-1 ultimately results in decreased cell growth. HGPRT/TBrHGPRT1-IN-1 is primarily used in the research of infectious diseases and cancer[1].
Formula: C15H24N6O9P2
References: [1]Cheshmazar N, et al. Key structural requirements of benzamide derivatives for histone deacetylase inhibition: design, synthesis and biological evaluation. Future Med Chem. 2024 Apr 16.