HL-8, CAS 2766352-64-9

Product Description: HL-8 is a PROTAC molecule targeting PI3K kinase. HL-8 has a significant and complete degradation effect on PI3K kinase at a concentration of 10 μM within 8 h. HL-8 has the potential for the research of cancer diseases[1].

Applications: Cancer-Kinase/protease

Formula: C57H59F2N11O9S2

References: [1]Wang H, et al. Design, synthesis and activity study of a novel PI3K degradation by hijacking VHL E3 ubiquitin ligase. Bioorg Med Chem. 2022 May 1;61:116707.

CAS Number: 2766352-64-9

Molecular Weight: 1144.27

Compound Purity: 99.17

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: PI3K

• SKU: MEXHY-143275-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-143275-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK