Product Description: HLE-IN-1 (Compound 4) is a human leukocyte elastase HLE inhibitor (Ki=1.8 nM). HLE-IN-1 is used in emphysema and inflammamry pulmonary research[1].
Formula: C8H6ClNO3S
References: [1]Hlasta, et al. A benzisothiazolone class of potent, selective mechanism-based inhibitors of human leukocyte elastase. Bioorganic & Medicinal Chemistry Letters, 4(15), 1801–1806.
CAS Number: 13947-21-2
Molecular Weight: 231.66
Research Area: Inflammation/Immunology
Solubility: 10 mM in DMSO
Target: Others